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Migraine is a common neurological disease, which can be chronic. According to the Migraine Research Foundation, symptoms include a severe throbbing recurring pain, usually on one side of the head and at least one of the following: “visual disturbances, nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch and smell, and tingling or numbness in the extremities or face.” Attacks tend to last between 4 and 72 hours. About 15% of the world’s population are affected by migraine, or around 1 billion people. In the United States and China, 39 million and 13 million people suffer from migraine, respectively. Furthermore, migraine disproportionately affects women. According to the WHO’s Global Burden of Disease Study published in 2010, the number of women who suffer from migraine is about three times that of men.
Qilu Pharmaceutical is one of the leading vertically integrated pharmaceutical companies in China, focusing on the development, manufacturing, and marketing of active pharmaceutical ingredients (APIs) and finished formulations. Qilu has 12 subsidiaries and 10 manufacturing sites worldwide. In 2910 it ranked eighth in the Chinese pharmaceutical industry by sales revenue. The company is actively looking for partnerships with global colleagues via in-/out-licensing and a co-development strategy.
Trend Interpretation | Is There Still a Clinical Future for TIGIT after Astellas quietly drops out of the race
Following PD-(L)1, high-end players have quickly joined the race to develop the new star T cell immunoreceptors with immunoglobulin and ITIM domain (TIGIT). Roche, BMS, Merck and other international pharmaceutical companies have all entered. Meanwhile, in China, BeiGene, Innovent Bio, Junshi Bio, Hengrui Medicine, and other companies are also contributing to TIGIT R&D. In 2020, both Innovent and BeiGene’s TIGIT antibodies successfully initiated clinical trials.
Part 2 of a series on the Analgesic Drug Market. Part 1 focused on China while Part 2 takes a global perspective.
Luye Pharma Group, a member of Luye Life Sciences Group, is an international pharmaceutical company focusing on drugs targeting the central nervous system (CNS), oncology, and other therapeutic areas. The company’s three main strategic priorities are global R&D, manufacturing, and the sale of innovative medications.
On October 26, Bayer announced a huge acquisition of Asklepios, which focuses on gene therapy, for US$4 billion. Following the trend of other international pharmaceutical companies such as Novartis, Roche, and Celgene, with this acquisition Bayer has also entered the cell and gene therapy track. Since 2018, there have been more than a dozen mergers and acquisitions of cell and gene therapy companies, and the momentum has not diminished. JW Therapeutics, which focuses on cell therapy, was also listed on the Hong Kong Stock Exchange on November 3.
In China, the rapid growth of the analgesic market is second only to oncology drugs. As an example, Yangtze River’s dezocine is an analgesic acting as a κ partial agonist and μ partial agonist. It leads the analgesics market in China with RMB 6 billion in sales. This article will attempt to give some of the history behind prescribing for pain, consequences of overprescribing, as well as showing some recent industry trends in China.
Schizophrenia, as defined by the NIH National Institute of Mental Health, is a “mental disorder characterized by disruptions in thought processes, perceptions, emotional responsiveness, and social interactions.” Symptoms of schizophrenia can be psychotic ones such as hallucinations, delusions, and thought disorder, but also may include, reduced emotional expression, reduced motivation to accomplish goals, difficulty in social relationships, motor impairment, and cognitive impairment.
According to the statistics of the World Health Organization, about 20 million people worldwide are plagued by the disease.
China Resources Pharmaceutical Group is the flagship subsidiary of China Resources Group (Ranks 79 on the 2020 Fortune Global 500 List), engaging in the R&D, manufacturing, distribution, and retail of a broad range of pharmaceutical and healthcare products.
On October 7, 2020, the high-profile 2020 Nobel Prize in Chemistry was announced. Emmanuelle Charpentier and Jennifer A. Doudna won the award for their discovery of CRISPR/Cas9, so called genetic scissors.
CRISPR is a gene editing tool that can be precisely targeted. Since its inception in 2012, the tool has contributed to many important discoveries in basic research, plant research, and medical research. It has been selected as one of the “Top Ten Scientific Breakthroughs in the World” by Science Magazine three times in 2012, 2013 and 2015.